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CSRM617 hydrochloride (CSRM-617) is a small-molecule inhibitor in the transcription element ONECUT2 (OC2) with Kd of 7.forty three uM in SPR assays, binds to OC2-HOX domain instantly; inhibits mobile progress and induced apoptosis in vitro in numerous Computer system mobile strains that expressed average to substantial levels of OC2; noticeably dow

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